Indian Drugs Database
List of drugs
Drug Information Database was created to simplify our search and to satisfy our inquiries. This database contains product specific information on medications approved for use in your country. It is worth mentioning that Drug Information Database is managed by government regulatory body concerning health and includes human pharmaceutical and biological drugs, veterinary drugs and disinfectant products; it contains approximately 15,000 products which companies have notified department of health as being marketed.
As a rule information available in the Drug Information Database consists of the following main parameters: brand name; description field; drug identification number (DIN); company; drug statuses; status date; class; active ingredient(s); strength; route(s) of administration; pharmaceutical form(s); product monograph (PM); schedule; therapeutic classification (AHFS and ATC); active ingredient group (AIG) number; veterinary species.
Patients should note that Drug Information Database is necessary for driving and supporting a person in the huge medical sphere by providing such drug databases within information systems. Usually the authors of these databases create a profitable partnership with the system developer customers to integrate the drug databases to improve user workflow, enhance clinical decision making at the point-of-need, and give a helping hand to reduce the incidence of medication errors and adverse drug events.
In general, Drug Information Database provides a client with the main facts and general knowledge about the chosen medications; it explains why they are used and some, but not all, of the possible side effects.
However, a person is to keep in mind that this guide should not be used as a substitute for a detailed discussion with your physician and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.
Racecadotril is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor. Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect?it reduces the secretion of water and electrolytes into the intestine.
A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy.
Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon).
Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.
Ibuprofen from the now outdated nomenclature iso-butyl-propanoic-phenolic acid) is a non-steroidal anti-inflammatory drug (NSAID) originally marketed as Brufen, and since then under various other trademarks (see tradenames section), most notably Nurofen, Advil and Motrin. It is used for relief of symptoms of arthritis, primary dysmenorrhea, fever, and as an analgesic, especially where there is an inflammatory component. Ibuprofen is known to have an antiplatelet effect, though it is relatively mild and short-lived when compared with that of aspirin or other better-known antiplatelet drugs. Ibuprofen is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system.
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. Cefepime hydrochloride was first marketed in 1994 and is currently marketed under various trade names including Maxipime, Maxcef, Cepimax, Cepimex, and Axepim. A 2007 meta-analysis suggested that when data of trials were combined, mortality was increased in patients treated with cefepime compared with other ??-lactam antibiotics. In response, the U.S. Food and Drug Administration performed their own meta-analysis which found that there was no mortality difference.
Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
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Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective.
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors. It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis (programmed cell death).
Doxapram hydrochloride (marketed as Dopram) is a respiratory stimulant. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate.
An alkaloid found with hyoscyamine (with which it is also isomeric) in henbane, and extracted as a white, amorphous, semisolid substance.
Desmopressin is a synthetic replacement for vasopressin, the hormone that reduces urine production during sleep. It may be taken nasally, intravenously, or as a pill. Doctors prescribe Desmopressin most frequently for treatment of diabetes insipidus or bedwetting.
In December 2007, US drug regulators banned using desmopressin nasal sprays for treating bedwetting, but said that desmopressin pills are still a safe bedwetting treatment for otherwise healthy patients. The regulators reviewed the drug after two patients using desmopressin nasal sprays died from hyponatremia, an imbalance of sodium levels in the body.
Information Not Available
Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide.
It is sold under the trade names Myambutol and Servambutol.
Ormeloxifene (also known as Centchroman) is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a non-hormonal, non-steroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it is currently marketed there under the trade name Saheli. Ormeloxifene has also been licensed under the trade names Centron and Sevista.
Atorvastatin (Lipitor, Pfizer), is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms.
Dicyclomine is an anticholinergic that blocks muscarinic receptors. Dicyclomine is known as dicycloverine hydrochloride in the UK. Dicycloverine has 72 per cent of the anti-muscarinic power of atropine. It was invented in the United States in 1947.
Dicyclomine is used to treat intestinal hypermotility, the symptoms of Irritable Bowel Syndrome (IBS) (also known as spastic colon). It relieves muscle spasms and cramping in the gastrointestinal tract by blocking the activity of acetylcholine on cholinergic (or muscarinic) receptors on the surface of muscle cells. It is a smooth muscle relaxant.
In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.
In the UK it is sold under the trade names: Merbentyl (containing 10mg dicycloverine) and Merbentyl 20 (containing 20mg dicycloverine).
It is also sold in the UK as part of a multi-ingredient preparation under the trade name Kolanticon (Peckforton Pharmaceuticals), which in addition to dicycloverine, contains an antiflatulent (simethicone) and two antacids (aluminium hydroxide and magnesium oxide).
It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada. it is sold under the trade names spasmo proxivon and spasmo plus in India.
Embramine is a histamine antagonist
Arginine vasopressin (AVP), also known as vasopressin, argipressin or antidiuretic hormone (ADH), is a hormone found in most mammals, including humans. Vasopressin is a peptide hormone which controls the reabsorbtion of molecules in the tubules of the Kidneys by affecting the tissue's permeability. It plays a key role in homeostasis, and the regulation of water, glucose and salts in the blood. It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the blood stream; however, some of it is also released directly into the brain.
Haemocoagulase used to decrease or stop bleeding in every clinical treatment, for example, in surgery, internal medicine???? ? obstetrics and gynecology, ophthalmology, ear-throat-nose, stomatology. It can also be used to prevent from bleeding, for example, before operation. This will decrease or avoid bleeding on the wound during the operation and after the operation.
Nateglinide is a drug for the treatment of type 2 diabetes. Nateglinide was developed by the Swiss pharmaceutical company Novartis.
Nateglinide belongs to the meglitinide class of blood glucose-lowering drugs.
Trimipramine (Surmontil, Rhotrimine, Stangyl) is a psychoactive drug of the tricyclic antidepressant (TCA) chemical class with antidepressant, anxiolytic, antipsychotic, sedative, and analgesic effects.
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.
Leflunomide is a medication of the DMARD type, used in active moderate to severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor.
Donepezil (also misspelled donezepil), marketed under the trade name Aricept by its developer Eisai and partner Pfizer, is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. Its binding to the acetylcholinesterase can be seen at Proteopedia 1eve. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5mg per day, which can be increased to 10mg per day after an adjustment period of at least 4 weeks.
Diclofenac (marketed as Voltaren and under a number of other trade names, see below) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in conditions such as arthritis or acute injury. It can also be used to reduce menstrual pain, dysmenorrhea. The name is derived from its chemical name: 2-(2,6-dichloranilino)phenylacetic acid.
In the United Kingdom, India, and the United States, it may be supplied as either the sodium or potassium salt, in China most often as the sodium salt, while in some other countries only as the potassium salt. Diclofenac is available as a generic drug in a number of formulations. Over the counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.
Terconazole is an anti-fungal medication, primarily used to treat vaginal fungal infections.
Cimetidine is a histamine H2-receptor antagonist that inhibits the production of acid in the stomach. It is largely used in the treatment of heartburn and peptic ulcers. It is marketed by GlaxoSmithKline under the trade name Tagamet (sometimes Tagamet HB or Tagamet HB200).
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist which accelerates gastric emptying and is used for the treatment of acid reflux, irritable bowel syndrome and functional dyspepsia.
The MMR vaccine is a mixture of three live attenuated viruses, administered via injection for immunization against measles, mumps and rubella (also called German measles). It is generally administered to children around the age of one year, with a second dose before starting school (i.e. age 4/5). The second dose is not a booster; it is a dose to produce immunity in the small number of persons (2?5%) who fail to develop measles immunity after the first dose.
It is widely used around the world; since introduction of its earliest versions in the 1970s, over 500 million doses have been used in over 60 countries. As with all vaccinations, long-term effects and efficacy are subject to continuing study. The vaccine is sold by Merck as M-M-R II, GlaxoSmithKline Biologicals as Priorix, Serum Institute of India as Tresivac, and sanofi pasteur as Trimovax.
It is usually considered a childhood vaccination. However, it is also recommended for use in some cases of adults with HIV.
L-DOPA (L-3,4-dihydroxyphenylalanine; Levodopa; Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc) is a naturally-occurring dietary supplement and psychoactive drug found in certain kinds of food and herbs (e.g. Mucuna pruriens, or velvet bean), and is synthesized from the essential amino acids L-phenylalanine (PHE) and L-tyrosine (TYR) in the mammalian body and brain. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. Aside from its natural and essential biological role, L-DOPA is also used in the clinical treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD).
Atenolol; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.
Nifedipine; Belongs to the class of selective dihydropyridine derivative calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
Paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used for the relief of fever, headaches, and other minor aches and pains, and is a major ingredient in numerous cold and flu remedies. In combination with non-steroidal anti-inflammatory drugs (NSAIDs) and opioid analgesics, paracetamol is used also in the management of more severe pain (such as postoperative pain).
Urofollitropin (brand names Bravelle, Fertinex, Follistim, and Gonal-F) is a purified form of follicle-stimulating hormone (FSH). FSH is important in the development of follicles (eggs) produced by the ovaries. Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. It is also used with in vitro fertilization methods. The dosage is adjusted to each individual's response.
Its side effects include breast tenderness, mild diarrhea, nausea, or vomiting, constipation and hot flashes.
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Albendazole is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in the body. It is effective (first line of treatment) against: Flatworms Flukes/trematodes Tapeworm/cestodes Echinococcosis Nematodes Hookworms Roundworms Whipworms Threadworms or pinworms In Africa albendazole (donated by GlaxosmithKline)is being used to treat lymphatic filariasis as part of efforts to stop transmission of the disease. In sub- Saharan Africa, albendazole in used in conjunction with ivermectin, and elsewhere in the world, the medicine is used in combination with diethylcarbamazine. In Brazil and another countries is used against giardiasis.
Hydroxyzine is a first-generation antihistamine of the piperazine class that is an H1 receptor antagonist. It was synthesized in the early 1950s. It is used primarily as an antihistamine for the treatment of itches and irritations, an antiemetic for the reduction of nausea, as a weak analgesic by itself and as an opioid potentiator, and as an anxiolytic for the treatment of anxiety.
Hydroxyzine preparations usually require a doctor's prescription, as do other potent antihistamines in many countries; whereas some countries allow hydroxyzine and all or most other antihistamines to be sold over the counter.
Even though it is an effective sedative, hypnotic, and tranquilizer, it shares almost none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons. Drugs related to hydroxyzine are cyclizine, buclizine, and meclizine and they share all or most of the benefits, indications, contraindications, cautions, and side effects of hydroxyzine. The second-generation antihistamine cetirizine is one of the metabolites of hydroxyzine.
Amphotericin B is a polyene antifungal drug, often used intravenously for systemic fungal infections.
Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names. Due to its numerous side-effects, these drugs are now rarely administered for clinical use. As a member of the xanthine family, it bears structural and pharmacological similarity to caffeine. It is naturally found in tea, although in trace amounts (~1 mg/L), significantly less than therapeutic doses. It is found also in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans.
Ginkgo also spelled gingko, also known as the Maidenhair Tree after Adiantum, is a unique species of tree with no close living relatives. The ginkgo is classified in its own division, the Ginkgophyta, comprising the single class Ginkgoopsida, order Ginkgoales, family Ginkgoaceae, genus Ginkgo and is the only extant species within this group. It is one of the best-known examples of a living fossil, because Ginkgoales other than G. biloba are not known from the fossil record after the Pliocene.
Extracts of Ginkgo leaves contain flavonoid glycosides and terpenoids (ginkgolides, bilobalides) and have been used pharmaceutically. Ginkgo supplements are usually taken in the range of 40?200 mg per day. Recently, careful clinical trials have shown Ginkgo to be ineffective in treating dementia or preventing the onset of Alzheimer's Disease in normal people.
In memory enhancement
Ginkgo has many alleged nootropic properties, and is mainly used as memory and concentration enhancer, and anti-vertigo agent. However, studies differ about its efficacy. The largest and longest independent clinical trial to assess ginkgo biloba?s ability to prevent memory loss has found that the supplement does not prevent or delay dementia or Alzheimer?s disease. Some controversy has arisen over the conclusions drawn by some studies that were allegedly funded by a firm which marketed Ginkgo.
Methylxanthines are phosphodiesterase inhibitors. Doxofylline is a new generation long acting oral methyxanthine derivative. Its mainly used for maintenance therapy in patients suffering with Asthma and Chronic Obstructive Pulmonary Disease (COPD)